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Basic Guide to Growing Mushrooms at Home

27 November 2025 at 02:00

The home cultivation of magic mushrooms is becoming increasingly common due to the rise in their consumption. Being an easy, fast and convenient crop, as well as profitable, more and more people are choosing to grow them at home. While it may sound complex at first, with the right instructions and materials it turns into a rewarding experience that’s within anyone’s reach.

Today we want to make things easy for you with this introductory guide, which covers the basic and most important aspects of cultivation so you can successfully harvest your mushrooms without setbacks or headaches. Let’s go!

Magic mushrooms, or monguis, are being used in different kinds of therapies

Growing mushrooms at home is relatively easy, especially if you keep a few key aspects in mind

General instructions on how to grow hallucinogenic mushrooms

Each brand offers its own instructions to customers on how to achieve abundant harvests of hallucinogenic mushrooms. Although we recommend following each brand’s instructions, there are certain parameters that are generic and can be applied to all grow kits. To begin, we’ll quickly show you how to grow a hallucinogenic mushroom kit or bag, and then we’ll go into detail on each of the points we’re about to discuss:

To grow hallucinogenic mushrooms at home, the first step is obviously to get a grow kit to cultivate. To do so, and especially if you need some extra information before deciding, you can visit our posts on magic mushroom varieties for beginners or magic mushroom varieties for experienced users.

Once the product arrives at home, you should take it to a place that’s as clean and hygienic as possible to open it, unless it’s a grow bag, in which case you shouldn’t open it at all, just leave it in a space with the right temperature, between 23 and 27 ºC.

Going back to the usual mushroom kits: the best option is to put them inside the bag that comes in the package (Mushbag) or in a mini-greenhouse. This will be the space that guarantees the right environmental conditions for fruiting: between 22 and 26 ºC and at least 80% humidity.

If you ensure these conditions and pay close attention to hygiene, in 15 to 35 days (depending on the variety) you’ll be able to collect your first magic mushrooms. These can be eaten fresh or dried for storage.

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So, after this speed-run on how to grow hallucinogenic mushroom kits, let’s go through it step by step and in detail:

Materials needed to start a magic mushroom grow

The materials needed to start this type of mushroom cultivation are:

  • The cultivation method (bag or mini-greenhouse)
  • A thermo-hygrometer
  • Heat source (if necessary): heating mat or tubular heater
  • Water
  • Sprayer/humidifier

Cultivation method: advantages and benefits of each one

The first step is to determine which cultivation method suits you best. Each has pros and cons, so you should choose the one that best fits your space and its environmental conditions. The most common methods are three: the Mushbag bags that come with mushroom kits, mini-greenhouses and ready-to-grow cultivation bags.

  • Mushbag bags: these are breathable bags where you place the cake so that it can fruit. They act as a climate system where humidity and temperature can be easily controlled. They are individual, one per kit, and usually come with the kits you buy.
  • Mini-greenhouses: mini-greenhouses are the next step towards a more controlled grow. It’s easier to regulate the climatic conditions and you can also cultivate a greater number of kits in the same place.
  • Cultivation bags: these are bags with the mycelium already inside, so you don’t need anything else, just temperature control. An example of this type is the
Tidal Wave Ape about to be harvested

The yields offered by Tidal Wave Ape are truly amazing

Recommended climatic conditions for hallucinogenic mushrooms

For growing this type of mushroom, the first step is to know which climatic conditions are required. The three essential parameters are temperature, humidity and ventilation.

  • Temperature: between 22 and 26 ºC.
  • Humidity: it must stay above 80% at all times. You can spray water on the inner walls of the bag or greenhouse to keep it high, for example when you air the kit daily.
  • Ventilation: ideally, open the bag for a few seconds every day to renew the air inside and prevent CO2 from building up.

It’s very important to stress that one of the main points to consider are sudden climatic changes, both in temperature and humidity. Magic mushrooms are quite sensitive to these and their growth can completely stall. Make sure their environment is as stable as possible!

Temperature: how to achieve it at any time of year

To reach the temperature needed to grow hallucinogenic mushrooms, different temperature control methods can be used, depending on the space and the time of year:

  • If you grow in summer, you’ll need a cool, well-ventilated space where the temperature never exceeds 27 ºC.
  • For winter cultivation, we offer ideal products to increase the heat in your grow space. If you’re working with small mini-greenhouses or bags, a heating mat is the ideal product. It keeps the temperature between 22 and 26 ºC. If you grow in larger mini-greenhouses or propagation tents, a tubular heater can be your best friend. There’s also the option of heated mini-greenhouses, which already include a built-in heating element.
Thermo-hygrometer with probe for temperature and humidity control

With a thermo-hygrometer with probe, it will be much easier to monitor temperature and humidity

Humidity in the grow space: tips and advice

Psilocybe Cubensis mushrooms require high humidity; as mentioned above, all brands recommend at least 80%. Each grow will need a different method depending on the space.

For Mushbag bags

  • Add a finger’s depth of water to the bottom of the bag, making sure the substrate doesn’t come into contact with it.
  • Spray water on the inner walls of the bag. It’s important not to spray directly on the kit once the primordia have appeared, as they could rot.
  • If the walls of the bag dry quickly, you need to spray more often. You can add more water to the bottom of the bag or close the zipper opening a bit more.

For mini-greenhouses or propagators:

  • Pour water into the bottom tray until it’s 3–4 cm deep. The heat from the heating mat will help evaporate this water and raise the relative humidity inside.
  • If the mini-greenhouse has ventilation windows, you can adjust their opening to achieve a stable humidity level, ideally around 80%.
  • To grow in propagation tents, either place a tray of water inside on which you can put the kit, or add a humidifier.

Finally, as mentioned earlier, keep in mind that sudden changes in temperature or humidity can slow down the development process.

A high level of humidity is crucial

Humidity is a key factor for the development of both the mycelium and its fruiting bodies, that is, the mushrooms (Image: Marco Allegretti)

Ventilation: how to keep your space well aired

Good air circulation helps remove accumulated carbon dioxide (CO2). Mushrooms, like other organisms, consume oxygen and produce CO2, and high concentrations of this gas can inhibit their growth. Ensuring proper ventilation is essential to keep a healthy growing environment.

Mushbag grow bags

It’s recommended to leave the bag partially open, about 1/3 of its length, to allow a continuous air exchange.

When you open it to spray water, take the opportunity to renew the air. You can squeeze the bag slightly to expel the “stale” air and let fresh air in before closing it again.

Keep in mind that you’re walking a fine line here: if the bag is too open, the kit can dry out or get contaminated.

Mini-greenhouses or propagators

In this case, the simplest way is to leave the vents open to achieve the desired humidity and ventilation level. As it’s a larger space, the air takes longer to become saturated with CO2, but it’s still recommended to open the mini-greenhouse periodically.

Hallucinogenic mushroom grow bags

This is a special case. Unlike traditional cakes, grow bags such as Mycobag are designed so that the bag itself acts as a controlled environment.

There’s no need to air or open the bag at any time during the grow, only to harvest. These hybrids can grow with high CO2 and barely any O2, which makes cultivation easier and reduces the chances of contamination since you don’t have to open the bag.

Mushrooms prefer a clean environment with little air draft

Keep your mushroom kits away from drafts to avoid contamination

Hygiene in hallucinogenic mushroom cultivation

Hygiene in mycological cultivation is a key factor for success, from the very start of the grow to post-harvest handling and preparation for consumption.

A clean, controlled environment significantly reduces the risk of contamination in mushroom kits, as contamination is usually caused by other fungi and bacteria. It can compromise the quality and safety of the mushrooms produced; it’s not advisable to consume them if they are contaminated.

Contaminating microorganisms compete with the mycelium for nutrients and, in most cases, are more aggressive and colonise the substrate more quickly, resulting in the loss of the grow.

Preventive hygiene practices

Personal hygiene

  • Wash your hands thoroughly or use disposable gloves before handling the mushrooms or their grow. If you use gloves, disinfect them once they’re on.
  • Wear a mask while handling the kit to reduce the chances of contamination.
  • Try not to touch the kit or breathe over it.

Work space hygiene

  • Keep your grow environment clean and tidy.
  • Regularly disinfect the work area and grow facilities with isopropyl alcohol.
  • Keep the kits away from drafts.
  • Disinfect all tools and equipment used.

During the grow

  • It’s important to use gloves and masks every time you open the mini-greenhouse or Mushbag, as this is the riskiest moment in terms of contamination.
  • Mushroom grow bags significantly reduce the risk of contamination because you don’t need to open the bag at any time during the grow, only to harvest.
Hygiene is essential for a trouble-free grow

With proper hygiene, your mushroom kits won’t get contaminated and will fruit without any issues

Post grow (harvest, drying and storage)

  • During harvest, wash your hands thoroughly or use gloves.
  • Handle the mushrooms carefully when picking them so as not to damage the substrate or mycelium, which could impair the following flushes.
  • Avoid harvesting too late, as the release of spores could contaminate the kit and make new fruitings more difficult.
  • Drying the mushrooms completely is essential to preserve their potency and prevent mould and problems during storage.

Dangers and most common mistakes during magic mushroom cultivation

The most common and significant problems that can arise during magic mushroom cultivation revolve mainly around contamination and control of environmental conditions. These can seriously affect the mushroom cake and reduce production, or in the worst cases kill the mycelium. Below are the most frequent issues and their triggers:

Contamination of the grow

This is the most important and frustrating problem for growers. Contamination is caused by other fungi that compete with the mycelium. These unwanted microorganisms are often more aggressive and colonise the substrate faster than the mushroom mycelium, resulting in the loss of the grow.

Contaminations usually appear as patches of strange colours and textures on the surface of the kit that are not the pure white of healthy mycelium. The patches can be dark, pink, orange, green, etc., and may be accompanied by an unpleasant smell.

It’s important to distinguish these contaminations from the bluish bruising that mycelium or the mushrooms themselves can show due to psilocybin oxidation.

The main cause of contamination in mushroom kits is the lack of hygiene in the space or from the grower: it’s crucial to consider factors such as the grower’s hygiene, the grow space (air and lack of a clean, controlled environment) and the tools used.

The post Basic Guide to Growing Mushrooms at Home appeared first on Alchimia blog.

Liquid mycelium and new MycoSupplies mushroom kits at Alchimia

18 November 2025 at 08:14

The world of mushroom cultivation continues to evolve, and MycoSupplies is establishing itself as one of the most innovative brands in the sector. This time, it presents two important new products designed for both novice and advanced growers: the new Albino Penis Envy and Mac Galactic mushroom grow bags, and a line of liquid mycelium that improves efficiency, colonization speed, and sterility control.

Furthermore, the brand is expanding its offerings with complete kits that combine liquid mycelium with monotub or grow bag systems. This represents a practical and professional solution that simplifies the entire mycological process from start to finish. These additions reinforce MycoSupplies’ —and Alchimia’s—commitment to quality, innovation, and responsible mycological research. Today, we’ll tell you all about these new products!

Mac Galactic from MycoSupplies offers very high performance

The results with Mac Galactic from MycoSupplies are amazing

MycoSupplies: quality, innovation, and safety in mushroom cultivation

Since its inception, MycoSupplies has established itself as a leading brand in the field of home and laboratory mushroom cultivation. Distinguished by its commitment to the quality, sterility, and traceability of each of its products, its philosophy combines scientific research with accessibility, bringing professional tools to those who wish to explore the fascinating world of fungi.

Each product from the brand is manufactured under strict microbiological control protocols. The purity of the mycelium and the absence of external contaminants are guaranteed. Furthermore, MycoSupplies maintains an educational and responsible approach: its solutions are designed to promote observation, learning, and mycological experimentation, always respecting the industry’s safety and ethical standards.

This constant pursuit of excellence has made the brand synonymous with trust, durability, and innovation. These are essential values in a field where precision and care for the environment are crucial to achieving optimal results.

Magic mushrooms for beginners

MycoSupplies expands its catalog with new Albino Penis Envy and Mac Galactic grow bags

As part of its commitment to innovation, MycoSupplies is launching two new ready-to-use magic mushroom grow bags, featuring varieties selected for their yield, resistance, and ease of fruiting: Albino Penis Envy and Mac Galactic. Both have been developed with high-quality sterile substrates and vigorous mycelium that ensures rapid and even colonization.

These bags are designed to offer a comprehensive and practical solution. They’re especially suitable for those seeking reliable results without the need for advanced equipment. Each unit features a ventilation system and microporous filter, facilitating air exchange and maintaining optimal humidity and temperature conditions throughout the process.

  • Albino Penis Envy (APE): a variety known for its robust structure, mycelial density, and genetic purity. Ideal for observation projects or advanced mycological research. Its effect is very potent—you’ve been warned!
  • Mac Galactic: stands out for its uniform colonization and adaptability to different environments, making it a versatile option for those seeking fast and stable growth. Its yield is exceptional.

Both additions reflect MycoSupplies’ effort to offer safer, more efficient, and accessible culture materials. Their goal is to optimize the user experience without compromising the scientific quality of the process.

Albino Penis Envy from MycoSupplies is potent and highly productive

Albino Penis Envy (APE) by MycoSupplies is an extremely potent strain

MycoSupplies Liquid Mycelium: Innovation and efficiency for experienced growers

MycoSupplies liquid mycelium represents a significant advancement in mushroom cultivation techniques. This format accelerates substrate colonization, reduces the risk of contamination, and increases control over growing conditions.

This is a sterile suspension of active mycelium in a liquid nutrient solution. This mycelium can be inoculated directly onto grains, substrates, or culture cakes. Unlike solid mycelium or traditional spores, liquid mycelium offers more uniform distribution and a higher mycelial expansion rate, shortening incubation times.

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Among its main advantages are:

  • Controlled sterility: each batch is produced in a laboratory environment with HEPA filtration.
  • Rapid colonization: the liquid solution enables more homogeneous inoculation.
  • Versatility: compatible with various media, bags, and monotub systems.
  • Technical efficiency: reduces material waste and facilitates experimental replication.

Thanks to these characteristics, MycoSupplies liquid mycelium has become a tool of choice for experienced growers, educational centers, and enthusiasts of applied mycology, who seek precision and reliability at every stage of the process. The varieties currently available in our store are:

  • Albino Penis Envy liquid mycelium
  • Golden Teacher liquid Mycelium
  • McKennaii liquid mycelium
  • B+ liquid mycelium
  • Mexican lLiquid mycelium
  • Cyanescens liquid mycelium

Differences between growing mushrooms with spores or with mycelium

Complete liquid mycelium kits with monotub or bag: efficient and controlled cultivation

For those seeking a comprehensive solution, MycoSupplies presents its new liquid mycelium kits, available in two configurations: a kit with a monotub system and a kit with a grow bag. Both are designed to offer a safe, clean, and high-performance growing experience.

Mycelium kits with monotubs are designed for users who want more direct control over environmental variables such as humidity, ventilation, and temperature. This format allows observation of mycelial development in a closed space, optimizing fruiting and minimizing the risk of contamination.

On the other hand, mycelium kits with grow bags offer an even simpler system, ideal for those seeking convenience without sacrificing quality. Their self-ventilating structure maintains a stable microclimate, reducing the need for external handling, which is especially useful in small spaces or without additional equipment.

Both options include high-purity liquid mycelium, prepared substrate, and support materials, forming a complete, ready-to-use mycological ecosystem. With these launches, MycoSupplies reaffirms its leadership in the sector, bringing technology, safety, and efficiency to all levels of experience.

B+ from MycoSupplies grown from liquid mycelium

The B+ harvests with MycoSupplies liquid mycelium are spectacular

MycoSupplies, advancing domestic mycology with precision and confidence

With these new additions, MycoSupplies reaffirms its commitment to excellence and safety in mushroom cultivation, offering solutions that combine scientific precision, ease of use, and superior quality, meeting the highest industry standards. Both the new Albino Penis Envy and Mac Galactic grow bags, as well as the liquid mycelium and complete kits, represent a step forward in the professionalization of home cultivation, bringing laboratory techniques to any responsible experimental environment.

In a context where applied mycology is gaining increasing interest, MycoSupplies positions itself as a benchmark in innovation, traceability, and training, providing products that not only optimize results but also promote a safe, ethical, and educational practice.

Discover the full range of MycoSupplies products at Alchimia Grow Shop and explore how mycological technology can transform the way we understand mushroom cultivation.

Happy harvest!

The post Liquid mycelium and new MycoSupplies mushroom kits at Alchimia appeared first on Alchimia blog.

Halloween Special: 4 terrifying recipes using Cannabis butter

28 October 2025 at 06:10

Halloween is fast approaching, and it’s the perfect opportunity to enjoy delicious and original recipes. This year, we’re going all out with a complete, 100% homemade menu…and with a magical touch, of course!

Made with cannabis butter, these dishes will surprise you not only with their delicious flavor but also with their appearance. Cannabis butter is the perfect base for infusing your savory and sweet dishes, and you can substitute it with olive or coconut oil for a vegan version. Today, we’ll teach you how to prepare it so you can cook these spectacular and terrifying delicacies.

On Halloween, sweets and recipes of all kinds are usually prepared.

Halloween is the perfect time to prepare original recipes

As we mentioned, cannabis butter is the perfect base for these recipes. Find out how to make cannabis butter quickly and easily by following the link. And if you’re vegan, you can try this vegan cannabis butter recipe; we assure you the result will be just as spectacular.

Once ready, you can store it in the refrigerator for several days or freeze it in portions, just like any other butter. Now, let’s move on to the recipes!

Witch’s Fingers Cheese Sticks

Witch fingers made with cannabis butter

Witch fingers are a perfect Halloween snack, and you can fill them with anything you want

As you’ll see, making these witch fingers with magic butter is really easy, and the results are simply spectacular! Let’s see what you’ll need and how you can make them in no time:

Ingredients:

  • 100 g of flour
  • 50g of cannabis butter
  • 50 g grated cheese (Emmental or Cheddar)
  • 1 pinch of salt
  • Whole almonds for nails

Preparation:

  • Mix all the ingredients (except the almonds) to form a shortcrust pastry.
  • Shape into sticks and then flatten the ends slightly to form fingers.
  • Place an almond on the end of each finger to make the nail.
  • Bake for 15 minutes at 180ºC.
  • Serve with a bright red tomato sauce (ketchup, tomato jam, etc.).

Puff pastry cookies with cheese and cannabis butter

Cannabis puff pastries are very easy to prepare

Ghost-shaped cannabis puffs

Ingredients:

  • 1 sheet of puff pastry
  • 50 g grated cheese (Emmental, Cheddar or Comté)
  • 2 tablespoons melted cannabis butter
  • 1 egg yolk (to brown the dough)
  • Some black olives for the eyes.
  • Salt, pepper

Preparation:

  • Preheat oven to 180°C.
  • Cut the dough with a ghost-shaped cookie cutter (or a knife).
  • Brush each shape with melted cannabis butter.
  • Sprinkle with grated cheese and then cover with another shape to ?close? the ghost.
  • Brush the outside of the ghosts with egg yolk.
  • Form the eyes with small pieces of black olive.
  • Bake for 15 to 20 minutes until golden brown.

Alchimia Tip: Serve them hot with a spicy ketchup ?blood.?

?Death?s Head? Tapas ? Mushrooms stuffed with cannabis butter

Although more laborious to prepare, the result is worth it.

The result of these mushrooms is truly striking

Ingredients:

  • 8 mushrooms
  • 2 tablespoons of cannabis butter
  • 1 clove of minced garlic
  • 40 g of breadcrumbs
  • 30 g grated Parmesan cheese
  • Fresh parsley
  • Salt, pepper

Preparation:

  • Remove the stems from the mushrooms and chop them.
  • Brown the garlic and chopped stems in the cannabis butter.
  • Add the breadcrumbs, Parmesan cheese, and parsley. Mix.
  • Fill the mushroom caps with this filling.
  • Bake in the oven for 15 minutes at 180ºC.

To achieve the ?skull? effect, draw the eyes and mouth with a small knife or black food coloring.

Visual Tip: Serve them over a green mash (spinach, peas, even guacamole) for a vibrant contrast.

Pumpkin and ghost meringue muffins

Cannabis muffins with meringue

Besides being delicious, these muffins are really visually appealing

Ingredients:

Muffins (pumpkin and spices):

  • 220 g pumpkin puree (well drained)
  • 180 g of T55 flour
  • 120 g of brown sugar
  • 1 large egg
  • 60g melted cannabis butter (warm)
  • 40 g of neutral oil (sunflower/rapeseed)
  • 8 g of baking powder
  • 1 pinch of salt
  • Spices: 1 teaspoon cinnamon, ½ teaspoon ginger, ¼ teaspoon nutmeg
  • 1 teaspoon vanilla extract
  • 60 ml of milk (or vegetable drink)

?Ghost? meringue:

  • 2 egg whites (? 70 g), at room temperature
  • 120 g of sugar
  • 35 ml of water
  • 1 pinch of salt
  • ½ teaspoon lemon juice

Decoration: mini chocolate chips or black edible gel for the eyes (and mouth)

Preparation

Muffin Dough and Baking:

  • Preheat the oven to 180°C (fan-assisted). Place the paper muffin cups in a baking pan.
  • In a bowl, whisk together pumpkin puree, sugar, egg, vanilla, melted cannabis butter (warm, not hot), and oil.
  • Sift the flour, baking powder, salt, and spices, then add them alternately with the milk. Mix until smooth (do not overwork).
  • Fill the boxes to ¾ of their capacity.
  • Bake for 20?22 minutes: a toothpick inserted should come out clean.
  • Let it cool completely on a wire rack (important before making the meringue).

Italian ?ghost? meringue:

Italian meringue holds up well, doesn’t grain, and turns into beautiful phantoms.

  • Syrup: In a small saucepan, heat the sugar and water to 118°C (small ball).
  • Meanwhile, begin whisking the egg whites with the salt and lemon juice at medium speed until a soft foam forms.
  • Pour the 118°C syrup in a thin stream over the egg whites while beating at medium-high speed. Continue beating for 4-5 minutes, until cool: the meringue should be glossy and firm.
  • Place the meringue on each muffin: using a plain round pastry bag (Ø 10?12 mm), form cones to create ghosts.
  • Bake for 5-7 minutes in the oven at 110°C or lightly torch for a golden brown finish (optional).
  • Add the eyes (sparkles/black gel) once the surface is warm.

Enjoy your meal, and Happy Halloween!

The post Halloween Special: 4 terrifying recipes using Cannabis butter appeared first on Alchimia blog.

A fungus hidden in Morning Glory seeds and its connection to LSD

27 October 2025 at 04:49

In a lab at West Virginia University (WVU), environmental microbiology student Corinne Hazel made a discovery that has captured the scientific attention: an elusive fungus, dubbed Periglandula clandestina, that lives in symbiosis with the seeds of the morning glory ( Ipomoea tricolor ). This discovery not only solves a mystery that has intrigued scientists for almost a century but also connects to the fascinating story of Swiss chemist Albert Hofmann, the creator of LSD, and the ancient use of these seeds in ethnobotanical practices. In this article, we will explore this discovery, its relationship to LSD, the role of these flowers in history, and the possible implications for modern science, including the growing interest in microdosing.

Join us on this journey into the world of fungi and plants!

The fungus Periglandula clandestina has been found in the seeds of the Ipomea tricolor

Ipomoea tricolor, variety ‘Heavenly Blue’ – Photo: Russell E, CC BY-SA 3.0

A fortuitous discovery with deep roots

Imagine a lab full of morning glory plants, with their vibrant blue flowers and tiny seeds. Corinne Hazel was studying how these plants disperse protective chemicals called ergot alkaloids through their roots. While examining the seeds, she noticed something curious: a bit of “fuzz” on the seed coats. “We had a bunch of plants lying around and these little seed coats,” Hazel said. “We noticed a little bit of fuzz on the coat. That was our mushroom!”

That “fuzz” turned out to be Periglandula clandestina, an endophytic fungus that lives inside the seeds of the morning glory in a symbiotic relationship. Hazel, working alongside Professor Daniel Panaccione, extracted a DNA sample from the fungus and sent it for genomic sequencing. The results confirmed it was a new species, and the genetic sequence now bears Hazel’s name in a gene bank. “Sequencing a genome is a significant thing,” Panaccione said. “It’s incredible for a student.”

This fungus is no ordinary discovery. For decades, scientists suspected that a fungal organism was responsible for the psychedelic compounds present in morning glory seeds, but no one had been able to identify it. Hazel and Panaccione finally solved this mystery, publishing their findings in the journal Mycologia (DOI: 10.1080/00275514.2025.2483634).

Corinne Hazel examining morning glory seeds

Corinne Hazel examining morning glory seeds – Photo: WVU Photo/Brian Persinger

The connection with Albert Hofmann and LSD

The story of Periglandula clandestina is intertwined with that of Swiss chemist Albert Hofmann, who in the 1930s synthesized LSD (from the German ?Lysergsäurediethylamid? ? lysergic acid diethylamide) from ergot alkaloids produced by the fungus Claviceps purpurea, which grows on grains such as rye. Hofmann noticed that bellflower seeds, particularly those of the species Ipomoea tricolor, contained compounds similar to those he had modified to create LSD, such as ergine (Lysergsäureamid amide or LSA). Intrigued by the traditional use of these seeds in Mesoamerican ceremonies, Hofmann hypothesized that a symbiotic fungus within the bells might be producing these psychedelic compounds. However, despite his efforts, he never found the mushroom in question.

Hofmann wasn’t wrong. Bellflower seeds contain derivatives of lysergic acid, which gives them their psychedelic properties. “This inspired Hofmann and others to investigate bellflowers for a hidden fungus related to the ergot fungus that could be the source of these chemicals,” Panaccione explained. “They found very similar chemicals, but they were never able to find the mushroom itself.” Hazel’s identification of Periglandula clandestina confirms Hofmann’s theory, showing that this fungus is, in fact, responsible for producing the ergot alkaloids in bellflower seeds.

Ergot and lysergic acid (LSD)

An ethnobotanical journey into the past

Bells aren’t just decorative plants; they have a rich ethnobotanical history dating back centuries. Mesoamerican peoples, such as the Aztecs, were familiar with the psychedelic properties of the seeds of the Ipomoea tricolor plant, which they called tlitliltzin or ololiuhqui. Similar to magic mushrooms, these seeds were used in spiritual and medicinal rituals, considered sacred for their ability to induce visions and altered states of consciousness. Shamans used them to communicate with the divine, heal illnesses, or explore the spirit world.

The knowledge of these properties did not go unnoticed by Hofmann, who studied the traditional uses of bells to better understand the chemical compounds they contained. The connection between ancestral use and modern science is fascinating: what indigenous peoples knew intuitively, science now confirms with the discovery of Periglandula clandestina. This mushroom, hidden in seeds, is the engine behind the psychedelic effects that have intrigued ancient and modern cultures alike.

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What are ergot alkaloids and why are they important?

Ergot alkaloids are chemical compounds produced exclusively by fungi, such as Periglandula clandestina and Claviceps purpurea. These compounds have a double face: in high doses, they can be toxic to humans and animals, causing a condition known as ergotism, which historically led to severe symptoms such as seizures, hallucinations, and even gangrene. However, in controlled doses or with their molecular structures modified (derivatives), ergot alkaloids have therapeutic applications. Currently, they are used in medications to treat migraines, uterine bleeding, dementia, and Parkinson’s disease.

Microdosing and morning glory seeds

In recent years, microdosing ?the consumption of very small doses of psychedelic substances to enhance creativityfocus, or well-being without inducing hallucinations ?has gained popularity. While microdosing with LSD or psilocybin (from psychedelic mushrooms) is more common, morning glory seeds, rich in LSA, have also been used by some enthusiasts. LSA has milder effects than LSD, but can induce states of relaxation and insight at low doses.

However, using morning glory seeds for microdosing is not without risks: ergot alkaloids can cause side effects such as nausea, vasoconstriction, or dizziness if not dosed correctly. Furthermore, seed preparation requires care, as some commercial varieties are treated with toxic chemicals.

The mystery of an endophyte: The secret life of Periglandula clandestina

Summary Poster: "A New Species of Fungus Symbiotic with the Morning Glory Ipomoea tricolor"

Summary poster: “A New Species of Fungus Symbiotic with the Morning Glory Ipomoea tricolor”. (Source: symposium.foragerone.com)

What makes Periglandula clandestina so fascinating is its nature as an endophyte, an organism that lives harmlessly inside another, in a symbiotic relationship. In this case, the fungus resides in the seeds of the morning glory, producing alkaloids that protect the plant from herbivores and disease. In return, the plant provides a safe home for the fungus. This relationship is a perfect example of how nature creates complex alliances for survival.

The name “clandestina” couldn’t be more appropriate. This fungus managed to evade scientists for decades, hidden in tiny seed coats. Hazel is now working on cultivating this slow-growing fungus in the lab, a crucial step toward studying its properties and potential applications.

A discovery that opens the door to future research

The story of Periglandula clandestina is more than a scientific discovery; it’s a bridge between the past and the future. It connects the ancestral knowledge of Mesoamerican peoples with the curiosity of Albert Hofmann and the perseverance of a student like Corinne Hazel. The discovery of Periglandula clandestina opens the door to exploring other species of morning glory, which could host other symbiotic fungi with unique compounds yet to be discovered.

In a world where psychedelic research is resurfacing, this discovery is a reminder that answers to big scientific questions are often hidden in the most unexpected places. From Mesoamerican ceremonies to modern laboratories, morning glory seeds and their hidden mushroom invite us to continue exploring the intersection of nature, science, and mental health.


References:

The post A fungus hidden in Morning Glory seeds and its connection to LSD appeared first on Alchimia blog.

7 varieties of mushrooms you should know

2 October 2025 at 04:43

What do Thai Pink Buffalo, Cascadian Teacher, and Penis Envy have in common? No, this isn’t the beginning of a bad bar joke, but rather a small sample of the psychedelic catalog you can find today in the form of magic mushroom cakes. What was extremely difficult to obtain in most places just a few decades ago is now sold legally in the form of a home grow kit, with complete growing instructions and the peace of mind of discreet shipping.

The rise of magic mushrooms is no coincidence: in a world where stress and disconnection have become the norm, more and more conscious explorers are looking to psilocybin for more than just a “trip”. They’re seeking transformative experiences, modern rituals that somehow connect with the ancient traditions of shamans and spiritual seekers, whether we’re talking about traditional doses or microdoses of psilocybin.

In this article, we’ll review seven mushroom varieties you should know about, available on the Alchimia website, and which offer a surprising range of potencies, effects, and experiences worthy of their name. Let’s get started!

Specimens of albino hallucinogenic mushrooms

Thanks to new research, magic mushrooms and their use are becoming increasingly accepted

Mushroom varieties you can’t miss

The world of psilocybin mushrooms is as diverse as that of cannabis strains. Each variety has its own nuances, both in its development and its effects: some are more visual, others more introspective, some give you endless laughs, and others immerse you in profound and transformative experiences of self-discovery.

In general, they all share a common denominator: psilocybin, a compound that temporarily alters the perception of reality, the senses, and consciousness. But depending on genetics and the growing environment, the nuances can vary greatly.

If you’re a beginner, it’s best to start with mild strains or those with more playful effects. If you’re already an experienced explorer, you might be drawn to other types of varieties that promise more potent and challenging experiences. Either way, below we present a series of genetics that every mushroom lover should try at least once in their life.

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Thai Pink Buffalo

This strain has an origin as picturesque as its name: according to legend, it was mycologist John W. Allen who first discovered these mushrooms on the island of Ko Samui, Thailand, not far from a pink buffalo reserve. Since then, the story has become part of its mythical aura. In practical terms, we’re talking about a medium-strength Psilocybe cubensis, ideal for those looking for a trip full of positive energy, easy laughter, and lively but not overwhelming visual effects. Thai Pink Buffalo is often recommended for social sessions or light exploration, as its effect combines a strong visual stimulus with a playful and festive state of mind. Perfect for those looking to try something exotic without jumping straight into the psychedelic abyss.

Tatandi's Thai Pink Buffalo Magic Mushrooms, easy to grow and potent

Thai Pink Buffalo magic mushrooms produce intense visual effects

Panaeolus cyanescens

Nicknamed “Copelandia cyanescens” in some circles, this mushroom is considered the elite of psilocybin. It grows naturally in tropical climates and is known for having one of the highest concentrations of psychoactive alkaloids. The effects are felt quickly: a burst of geometric visualizations, intense sensory distortions, and a sense of ego dissolution that can be as fascinating as it is challenging. Panaeolus cyanescens is not a strain recommended for beginners, as its potency requires experience and respect. In the right environments, it can lead to transformative, almost spiritual experiences, where the perception of time and space dissolves.

Super Natalensis

“Natalensis” was already known among psychonauts for its expansive nature and ability to induce heightened states of consciousness. The Super Natalensis version takes that reputation even further, offering trips that combine mental clarity with a deep sense of connection to one’s surroundings. Unlike other, more visual varieties, this one stands out for its introspective effect, accompanied by pleasant bodily sensations and spontaneous laughter. Many consider it an ally in therapeutic processes or spiritual self-exploration, as it tends to open the mind without the aggressiveness of other, more “chaotic” strains. A balanced mushroom that combines potency with harmony.

Super Natalensis hallucinogenic mushrooms are easy to grow

Tatandi’s Super Natalensis stand out for their high power

Penis Envy

The name alone is enough to arouse curiosity: Penis Envy was named for the peculiar phallic shape of its fruiting bodies and their large size. But what’s truly relevant is that it’s one of the most potent cubensis ever developed, with a higher-than-average psilocybin level. Its trips are often profound, prolonged, and transformative, with a strong introspective component that can border on the mystical. It’s not uncommon to hear testimonials from users who describe these experiences as “a before and after.” However, caution is advised: due to its potency, it’s not the best option for beginners, but rather for those seeking a serious, intense, and cathartic experience.

Melmac Thrasher

This strain is a direct descendant of the Penis Envy lineage, but with a distinct personality reflected in both its twisted appearance and its effects. The deformed hats and irregular aesthetic already hint at the type of trip it offers: potent, unpredictable, and with a chaotic component that fascinates those seeking more than just a “good vibe.” Melmac Thrasher‘s effects can range from uncontrolled laughter, intense visual patterns, and moments of deep reflection, all in one trip. It’s a strain for the adventurous spirit, those who enjoy the unexpected and aren’t afraid of being shaken up by the experience.

Melmac Thrasher magic mushrooms are very potent, for experts only.

Melmac Thrasher is an extremely powerful hybrid of Penis Envy and Melmac

Jedi Mind Fuck

Its name sounds like something out of a Star Wars fan joke, but its effects are anything but. Jedi Mind Fuck is a medium-to-high potency cubensis known for inducing deeply mental experiences, laden with abstract visuals and sensations of consciousness expansion. Its character is more balanced than that of Panaeolus cyanescens, but with enough power to offer memorable trips. It is often recommended for both intermediate explorers and experienced psychonauts looking for a balance between fun and serious exploration. Ideal for creative sessions, as it tends to enhance imagination and symbolic perception.

Cascadian Teacher

Of more recent origin, this strain has gained popularity for its balance of approachability and depth. Its name refers to the Cascadia region (northwestern United States and Canada), and to one of its likely parents, the legendary Golden Teacher, to which many users associate its effects. The trip it proposes is clear, visually harmonious, and emotionally positive, making it a great choice for those seeking revelatory experiences without having to confront the overwhelming power of strains like Penis Envy or Panaeolus cyanescens. Cascadian Teacher teaches, guides, and accompanies, rather than dragging or confronting. For this reason, many consider it an ideal mushroom for beginners looking for a transformative yet gentle experience.

Cascadian Teacher performance can be very high

Impressive performance of a Cascadian Teacher grow bag

From the legendary Thai Pink Buffalo to Cascadian Teacher, these varieties are just a small sample of the richness and diversity of the magic mushroom universe. The curious thing is that, while governments and laws continue to debate the merits of prohibition, regulation, and therapeutic uses, in practice, more and more people are finding direct access to experiences through a simple home grow kit that were once reserved for shamanic rituals or underground circles just a few decades ago.

Contradiction? Absolutely. But it’s also a sign that magic mushrooms have ceased to be taboo and have become a tool for personal, cultural, spiritual, and even therapeutic exploration, as evidenced by the latest studies on psilocybin and conditions like depression and post-traumatic stress disorder. And who knows? Perhaps in the near future we’ll be talking about them not as “magic mushrooms,” but as part of a new way of understanding well-being and consciousness.

Happy trip!


References:

  • Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms, Robin L Carhart-Harris, Leor Roseman, Mark Bolstridge, Lysia Demetriou, J Nienke Pannekoek, Matthew B Wall, Mark Tanner, Mendel Kaelen, John McGonigle, Kevin Murphy, Robert Leech, H Valerie Curran, David J Nutt
  • Efficacy and safety of psilocybin-assisted treatment for major depressive disorder: Prospective 12-month follow-up, Natalie Gukasyan, Alan K Davis, Frederick S Barrett, Mary P Cosimano, Nathan D Sepeda, Matthew W Johnson, Roland R Griffiths
  • Psilocybin for Trauma-Related Disorders, Amanda J Khan, Ellen Bradley, Aoife O’Donovan, Joshua Woolley
  • Psychedelic-Assisted Therapy for PTSD, Leslie Morland, Joshua Woolley

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This is how psilocybin affects your brain

19 September 2025 at 03:32

For centuries, different cultures have turned to so-called “magic or hallucinogenic mushrooms” not only as a vehicle for spiritual connection, but also as a healing tool. What was once considered an ancestral ritual is now capturing the attention of modern neuroscience. The reason? A compound called psilocybin, capable of altering perception, modulating brain activity, and, with increasing scientific support, offering relief from disorders such as depression and anxiety.

As research on psychedelics gains a foothold in clinical settings, it’s crucial to understand how this substance acts in the brain. What mechanisms does it trigger? Which brain regions does it affect? Can its effects really be compared to those of conventional antidepressants? In this article, we aim to shed light on these and other questions by analyzing the most recent studies. Will you join us?

Psilocybin acts on different areas of the brain

Psilocybin affects your brain in different ways. Today, we tell you how (Image: David_SMC)

Psilocybin, the main psychoactive component of magic mushrooms

Psilocybin is a tryptamine alkaloid found in more than 180 species of mushrooms of the genus Psilocybe, among others. After ingestion, the body rapidly converts it into psilocin, the active metabolite responsible for its psychoactive effects. This molecule, structurally similar to serotonin, can cross the blood-brain barrier and act directly on neuronal receptors.

Although psilocybin’s popularity rose in Western culture during the 1960s counterculture era, thanks to figures like Timothy Leary and pioneering research at Harvard, its use dates back to pre-Columbian times. Mesoamerican civilizations, such as the Aztecs, already used these mushrooms for religious and medicinal purposes, under the name teonanácatl (“flesh of the gods”).

Today, far from the stigma, psilocybin is being re-evaluated by the scientific community, with studies pointing to its therapeutic potential in very specific and controlled contexts. From clinical trials on drug-resistant depression to research on its ability to induce neuroplasticity, this molecule is now enjoying a second life, albeit with a white coat, microscope, and science as its backdrop.

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Psilocybin and the brain

Receptors involved: the role of serotonin

The primary target of psilocin (the active metabolite of psilocybin) in the brain is the 5-HT2A receptor, a subclass of serotonin receptors. This receptor is widely distributed in the prefrontal cortex, a region associated with higher cognitive functions such as abstract thinking, decision-making, and emotional regulation.

When activated, these receptors trigger a cascade of signals that alter the brain’s normal dynamics. Far from being limited to a simple “increase” in serotonin, what occurs is a profound reconfiguration of brain activity, involving multiple neural networks.

Interaction with dopamine and other neurotransmitter pathways

Although psilocin’s most prominent effect is through the serotonergic system, there are indirect interactions with other neurotransmitters, such as dopamine. Some studies suggest that 5-HT2A activation can modulate dopamine release in areas such as the striatum or the mesolimbic circuit, which are involved in reward and motivation.

This interaction could help explain the subjective sense of “insight” or inner discovery that many users experience, as well as certain changes in emotional processing.

Relationship with the amygdala: fear, anxiety, and emotional response

The brain’s amygdala, the nerve center for processing fear and anxiety, shows reduced activity under the influence of psilocybin. This has been demonstrated in functional neuroimaging studies, which show a decreased reactivity of this structure to negative or threatening stimuli.

This phenomenon could be behind the anxiolytic effects observed in patients with disorders such as depression or generalized anxiety disorder. Rather than “blocking” emotions, psilocybin appears to facilitate a more flexible approach to emotional experience.

Fractal images are often observed under the effects of psilocybin

When taking psilocybin, it is not uncommon to see fractal-like images when you close your eyes (Image: BarbaraAlane)

Brain network desynchronization: the “default mode” and beyond

One of the most consistent findings in recent psychedelic research is the temporary dissolution of the Default Mode Network (DMN), a brain network that activates when we are mentally at rest, ruminating, or focusing on ourselves. Under psilocybin, this network loses its usual coherence, which is associated with the experience of “ego dissolution,” so commonly reported by a large number of users.

At the same time, increased connectivity is observed between brain regions that don’t normally communicate with each other, resulting in a freer, less hierarchical pattern of neuronal activity. In other words, the brain stops following its usual highways and explores secondary paths, with results as varied as they are revealing.

Brain cell growth: neurogenesis and plasticity

One of the most promising discoveries concerns neurogenesis and neuroplasticity. Animal models and human visualization tools have shown that psilocybin can stimulate the growth of new synaptic connections and promote neuronal branching, especially in the prefrontal cortex.

This effect could underlie its therapeutic potential, as depression and other mental disorders are often associated with reduced brain plasticity. Thus, psilocybin not only momentarily alters perception but could also open a “window of opportunity” for long-term psychological restructuring.

Long-term effects: lasting changes?

Although the subjective duration of a psilocybin trip is typically limited to a few hours, its long-term effects can persist for weeks or even months. Longitudinal studies have shown sustained improvements in mood , a reduction in depressive symptoms, and greater psychological openness in participants.

These effects appear to be mediated, at least in part, by functional changes in brain connectivity and a new way of processing thoughts and emotions, even after the substance has been eliminated from the body.

Brain anatomy

Different areas of the brain

How does psilocybin affect your mood?

One of psilocybin’s most notable effects is its ability to modulate an individual’s emotional state, even long after it has left the body. Far from being a simple “high,” its impact on mood responds to a combination of neurobiological and psychological factors acting at different levels.

During the acute experience, many people report a significant increase in well-being, a sense of deep connection with oneself, others, or one’s environment. Clinically, this experience can translate into a reduction in negative affect , increased tolerance for unpleasant emotions , and a more open attitude toward psychological distress.

One of the key mechanisms here is the alteration of emotional processing. Psilocybin appears to facilitate a kind of affective “reset,” in which repressed or bottled-up emotions can surface, be processed, and released. In clinical studies, participants have been observed not only to experience an improvement in their overall mood but also to re-evaluate painful memories with less emotional baggage, which can have a lasting therapeutic effect.

For people with depression, this ability to reconnect with the emotion without getting caught up in it is especially valuable. As some patients in clinical trials have described, “It’s not that the sadness disappears, it’s that it no longer has the same power over me.”

Furthermore, increased cognitive flexibility has been identified after psilocybin use, a change that translates into less mental rigidity and greater openness to new perspectives. This phenomenon, difficult to quantify but consistent across multiple studies, could explain why many people report experiencing “a new way of seeing life” after a single controlled session.

It’s important to remember that the effects on mood are neither automatic nor universal. The quality of the psychedelic experience depends on multiple factors, from the dose to the setting and therapeutic support (set & setting). In clinical contexts, these elements are carefully considered precisely to enhance the benefits and minimize the risks.

Introduction to microdosing psilocybin

Psilocybin as a substitute for antidepressants?

The possibility that a single or a few doses of psilocybin could have effects comparable to—or even superior to—weeks of treatment with traditional antidepressants has generated enormous interest in the medical community. And with good reason. In a context where major depression remains one of the leading causes of disability worldwide, the search for more effective therapies with fewer side effects is a priority.

Studies such as those conducted by Imperial College London and the NYU Langone team have shown that psilocybin, administered in controlled settings and with therapeutic support, can significantly reduce depressive symptoms in patients with treatment-resistant depression. In some cases, improvement persists for weeks or months after a single session.

One of the key differences with conventional antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), is the mode of action. While SSRIs act chronically, artificially elevating serotonin levels in the synapse, psilocybin appears to reactivate deep emotional mechanisms and stimulate neuroplasticity, paving the way for psychological restructuring that doesn’t depend on continuous use.

Furthermore, patients often describe a qualitatively different improvement. It’s not simply that they “feel less sad,” but rather that they regain interestemotional connection, and the ability to experience pleasure —aspects that SSRIs often fail to fully restore.

Psilocybin is being studied in psychological support contexts

The use of psilocybin is helping patients find that missing piece (Image: reidy68)

On the other hand, we must be cautious: this is not a magic bullet, nor is it intended for home or recreational use. Psilocybin alone does not replace therapeutic support, and its transformative potential requires a structured environment, with prior preparation and follow-up. It is a powerful tool, but not a stand-alone tool.

To this day, clinical trials continue to accumulate evidence, and some regulatory agencies—such as the FDA in the US and the Paul Ehrlich Institute in Germany—have already granted these treatments “breakthrough therapy” status. Are we witnessing the future of psychiatry? It’s too early to say, but the cards on the table invite us to look beyond the traditional prescription.

Combined use of psilocybin and other drugs

Although psilocybin is relatively safe in controlled clinical settings, combining it with other substances can be problematic. Combining it with antidepressants, especially SSRIs, can reduce its effect or, in rare cases, cause serotonin syndrome. Therefore, in clinical trials, conventional medications are often discontinued before administering them.

Recreational use with other drugs such as cannabis, MDMA, or alcohol increases the risk of adverse reactions, such as intense anxiety, confusion, or unwanted physical effects; in other words, what is considered a bad mushroom trip. Furthermore, people with a history of psychotic disorders should avoid use, as it can trigger serious episodes.

In short, Psilocybin is not a substance to be mixed without medical knowledge or supervision. Interactions can be unpredictable and, in some cases, dangerous.

Bad trips and magic mushrooms

Psilocybin for the treatment of addictions

Various clinical studies, such as those at Johns Hopkins, have shown that psilocybin, in combination with therapeutic support, can help patients overcome addictions such as alcohol, tobacco, or opiates. How does it do this? By facilitating deep introspective experiences that allow patients to review their behavior from a different perspective, with less judgment and more clarity.

At the brain level, it acts on reward and habit circuits and promotes neuroplasticity, which facilitates the learning of new behavior patterns. Important: it is not a detoxifier or a magic cure. It only works well in controlled clinical settings and with psychological support.

Bottom line: Psilocybin doesn’t magically eliminate addiction, but it can be a powerful tool to help break compulsive cycles when traditional treatments aren’t enough.

Psilocybin may help in the treatment of various addictions

Psilocybin is also being studied for the treatment of addictions

In just a few decades, psilocybin has gone from being viewed as a remnant of the counterculture to occupying a prominent place in neuroscience and psychiatry laboratories. And it has done so with good reason: accumulating data shows that its ability to modulate brain activity, unlock rigid emotional patterns, and promote neuronal plasticity make it a serious candidate for the treatment of complex disorders such as depression, anxiety, and addiction.

However, it’s important not to be carried away by unqualified enthusiasm. Psilocybin is not a panacea, nor is it without risks. Its therapeutic potential is only fully realized when administered with clinical rigor, in prepared settings, and with a deep understanding of the patient’s psychological context. It’s not so much a pill that magically cures, but rather a new door that opens… as long as you know how and when to cross it.

With each new study, we learn more about the brain, but also about ourselves. And perhaps that’s the most interesting thing: that, at its core, what psilocybin seems to offer us isn’t answers, but the possibility of asking the right questions.

Let the investigation continue!


References:

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A psychedelic revival: Psilocybin approved in Germany

17 September 2025 at 03:59

What if the keys to healing the deepest wounds of the mind were hidden in substances we’ve demonized for decades? In July 2025, Germany took a revolutionary step by becoming the first country in the European Union to approve a compassionate use program for psilocybin —the active ingredient in magic mushrooms—to treat treatment-resistant depression.

This milestone, led by the Central Institute of Mental Health (ZI) in Mannheim and the OVID Clinic in Berlin, is not just a medical breakthrough: it’s a call to rethink our relationship with psychedelics in a society that has divided “good drugs” from “bad drugs” with alarming hypocrisy. In Alchimia, we explore how this program underscores the importance of set (mindset) and setting (environment), transforming powerful tools like psilocybin into healing allies.

Imagine millions of people struggling with depression that doesn’t respond to conventional antidepressants or standard therapies—20-30% of cases in Germany and worldwide. Wouldn’t it make sense to explore other treatment options?

Germany leads the way toward responsible and compassionate use of psilocybin

Compassionate use program for psilocybin approved in Germany

The use of Psilocybin in therapeutic contexts

For these patients, life becomes a cycle of hopelessness. Here is where psilocybin comes into play, a natural compound found in magic mushrooms that acts on serotonin 5-HT2A receptors in the brain, inducing altered states of consciousness that can dissolve rigid thought patterns and open doors to new emotional perspectives.

Is it not magic, or is it? Studies such as the EPIsoDE, conducted by ZI Mannheim in collaboration with the Charité Berlin and the MIND Foundation, have shown that high doses of psilocybin (such as 25 mg, which would be roughly equivalent to 2.5 g of dried mushrooms) combined with psychotherapy can lead to positive responses in around 30% of participants.

The program, approved by the Federal Institute for Drugs and Medical Devices (BfArM) on July 11, 2025, allows the use of psilocybin (supplied as PEX010 by the Canadian company Filament Health) in exceptional cases. Eligible patients are adults with drug-resistant depression, with no viable approved treatment options and no opportunity to participate in clinical trials.

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Of course, the therapy is conducted in controlled settings: inpatient in Mannheim and at the day clinic in Berlin, with preparatory sessions, supervised administration, and intensive psychotherapeutic follow-up. “In selected cases, the therapeutic use of psilocybin can be a medically and ethically viable option, always under strictly controlled conditions,” says Prof. Dr. Gerhard Gründer, the program’s pioneer.

Dr. Andrea Jungaberle, OVID’s medical director, emphasizes: “It is not administered in isolation, but as part of a comprehensive approach that considers the patient’s psyche, body, and life context.”

A challenge to our modern prejudices

But let’s go beyond the scientific facts: this breakthrough forces us to confront the hypocrisy of our era. Why have we stigmatized psychedelics as “bad drugs” while embracing synthetic opioids or antidepressants with serious side effects? The dominant narrative, born of the moral panic of the 1960s and 1970s, ignores that indigenous cultures have used these substances for millennia in healing rituals and vision quests guided by a carefully designed mindset and environment, often accompanied by shamans.

Microdoses of psilocybin can be used, but also higher doses

Whether with normal doses or microdoses, studies on psilocybin and mental health continue

Today, in a society obsessed with productivity and control, we’ve forgotten that true mental health isn’t just about suppressing symptoms, but about exploring our inner selves to find purpose and connection. What if psychedelics, used responsibly, can help us break through modern isolation, fostering empathy and collective resilience?

Of course, the program is not without risks; it can induce acute anxiety or, rarely, psychotic episodes if not managed properly, so patients predisposed to psychosis are excluded. Furthermore, at least for now, it is temporary (until July 2026) and limited, with demand likely to outstrip supply, as has happened in Switzerland.

However, it represents an interesting paradigm shift: from prohibition to responsible integration. The data collected will drive Phase III studies, potentially accelerating psilocybin’s full approval in Europe, following the path of the U.S.

This moment inspires us to dream of a future where psychedelics are not taboo, but tools for a more compassionate society. Germany shows us that change is possible: by challenging prejudices, we open doors to innovation. Are we ready to rewrite history, recognizing that the power of these substances lies in how they are used? At Alchimia, we believe so, and this is just the beginning of a psychedelic renaissance that could transform our understanding of the human mind.


Sources:

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How to grow mushrooms at home: The Basics

9 July 2025 at 03:46

Growing magic mushrooms at home is becoming increasingly common due to the rise in their consumption. Because it’s easy, quick, and convenient, as well as profitable, more and more people are opting for home cultivation. While it may sound complex at first, with the right instructions and materials, it becomes a rewarding experience within everyone’s reach.

Today, we want to make things easier for you with this introductory guide, which covers the basic and most important aspects of growing so you can successfully harvest your mushrooms without any setbacks or headaches. Let’s get started!

Magic mushrooms of the Golden Teacher variety

Getting great harvests of mushrooms like these Golden Teachers is in your hands

General instructions on how to grow magic mushrooms

Each brand offers its buyers instructions on how to achieve abundant magic mushroom harvests. Although we recommend following each brand’s instructions, certain general guidelines can be applied regardless of the growing method chosen.

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To grow magic mushrooms at home, the first step is obviously to find a mushroom cake. To do this, and especially if you need some extra information to help you decide, you can visit our posts on magic mushroom varieties for beginners or magic mushroom varieties for experts. If you’re just starting, you basically have two options when it comes to growing mushrooms: the first is to choose mushroom cake kits, which come with a plastic container that houses the mycelium and which you’ll place inside a bag (included in the kit) or in a small greenhouse.

Alternatively, as a second option, you have grow bags that come pre-filled with mycelium and ready to fruit, such as Mycobag. This option is even more convenient, as you basically just need to make sure you place the bag in a suitable location. In any case, whichever method you choose, there are some parameters you should keep in mind:

Whitebilly from Mycobag

With grow bags like Mycobag, you just have to wait to harvest your mushrooms

• Temperature: between 22 and 26 ºC.
• Humidity: It must be above 80% at all times. You can spray water on the inside of the bag or propagator walls to keep it high, for example, when you air the cake daily (this step isn’t necessary if you grow with Mycobags or similar bags, only if you use the bag that comes with the kit or if you’re using a plastic propagator).
• Ventilation: It’s best to open the bag for a few seconds each day to refresh the air inside and prevent CO2 buildup. Again, you’ll only need to vent your bag if you’ve chosen the kit with a plastic container. The bags that already contain mycelium have a ventilation port to facilitate gas exchange, so there’s no need to open them until harvest day.

Once the product arrives home, the first step is to decide where you’re going to grow. Choose a location with temperatures similar to those indicated, preferably with indirect light. Never place your grow kits or bags in full sun! If possible, and to avoid possible contamination, try to keep them as far away from the ground and away from drafts as possible. Let’s now look at how to grow them depending on the method you’ve chosen:

Growing magic mushrooms in a kit

Growing mushrooms with Tatandi or Freshmushrooms grow kits is simple and profitable

Growing magic mushrooms with grow bags

As we’ve mentioned, growing with grow bags like Mycobag, which already have the mycelium ready to fruit, is the easiest option. Simply keep the closed bag in a space between 22 and 26°C with indirect light. The mycelium will soon begin to form primordia, which will turn into fully developed mushrooms in just a few days.

When you see that most of your mushrooms are beginning to open their caps, it’s the ideal time to harvest them, before the veil completely breaks and they release their spores. Disinfect your hands well (or your nitrile gloves if you’re using them) and proceed to open the bag and carefully remove the mushrooms from their bases, rotating them slightly to facilitate harvesting.

You can eat your mushrooms fresh, although they’re usually dried and stored in airtight containers. The refrigerator is an ideal place to store them.

Harvesting, drying and storing magic mushrooms

Growing magic mushrooms with grow kits

This option includes mushroom cake kits from brands like Tatandi or Freshmushrooms, which actually come with instructions that you can also find on this blog. Let’s see how to proceed step by step to harvest them without problems:

  • 1.- Thoroughly disinfect the surface where you are going to work, as well as your hands or gloves.
  • 2. Remove the lid from the plastic container and place it inside the bag included in the kit, or in a small propagator. This will ensure the right environmental conditions for fruiting: between 22 and 26°C and a minimum of 80% humidity, with indirect light.
Disinfect everything before you start handling the kit.

Remove the lid from the kit and place it inside the included bag

  • 3.- To maintain these conditions, you’ll likely need a water mist sprayer and a heating mat, depending on the time of year. Make sure to ventilate the bag daily by opening it for a few seconds and taking the opportunity to spray water on its interior walls. This will help maintain high humidity.
  • 4. After 15 to 35 days (depending on the variety), you should harvest your first magic mushrooms. They should be picked when the cap begins to open, but the veil has not yet broken. When harvesting, be very careful not to break the growth layer and thus affect future harvests. Yes, after this first harvest, you can make more flushes by following the instructions in your kit!
Mushrooms will not grow well in direct sunlight.

Close the bag tightly and leave it somewhere with a good temperature and indirect light

  • 5.- Dry the mushrooms in a cool, dark, and airy environment until they break when bent.
  • 6.- Try to keep magic mushrooms in a glass jar or vacuum-sealed in a cool, dark place.
Try to harvest your mushrooms before they release spores.

After a few days, your mushrooms will be ready to harvest

The post How to grow mushrooms at home: The Basics appeared first on Alchimia blog.

Growing mushrooms in a propagator with a heating mat

25 June 2025 at 03:36

There comes a time in every home mushroom grower’s journey when plastic trays, radiator heat, and makeshift bags fall short. It’s not that they don’t work—on the contrary, they’re the perfect gateway—but there comes a point where, if we truly want to improve results and professionalize our cultivation, we need to take a step further.

That step has a name, and it’s the one most growers take when they want to improve the yield of their mushroom batches: propagator + heating mat. An unbeatable duo that allows for better environmental control, stabilizes conditions, and, most importantly, reduces risks and increases harvest weight. If you’ve been growing your mushrooms for a while and are curious to take things a step further, read on. This might interest you.

Fruiting mushroom cake

Achieving good fruiting is easier with a propagator and a heating mat

Growing mushrooms at home: the basis of the amateur mycologist

Growing mushrooms at home isn’t (just) for hippies or laboratory freaks. It’s an exciting, rewarding, and surprisingly accessible activity these days. But beware, it’s also subtle, delicate, and somewhat capricious. A poorly controlled or incorrectly optimized factor can ruin your crop, so it’s best to make sure your mushrooms enjoy the best possible conditions during their short lifespan to ensure results that will put a huge smile on your face.

Here, it’s not enough to just leave your kit or bread anywhere and cross your fingers. For mushrooms to thrive and show their full potential, certain factors must always be respected. If you’ve grown mushrooms before, you’re probably familiar with them, but let’s go over them anyway:

  • Hygiene: This is the first rule. From cleaning the environment to your hands and utensils. Contamination is the number one enemy of cultivation.
  • Humidity: Mushrooms love moisture, but not puddles. The ideal environment is usually around 80-85% relative humidity.
  • Temperature: Each species has its preferences, but most thrive comfortably between 20 and 25°C.
  • Ventilation: Your mushrooms don’t like stale air. Gentle circulation is essential to prevent CO₂ buildup in the growing environment, whether it’s a bag or a small plastic greenhouse.
  • Indirect light: Mushrooms don’t need sunlight, but they do need a clear light/dark balance to grow normally. Any spot with indirect light will do.

With this under control, growing mushrooms at home can become a ritual as comforting as cooking or tending your plants. But let’s now look at how to do it using a plastic propagator and a heating mat, which is one of the most widely used systems by growers around the world, given the excellent results it offers.

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Propagator and heating mat: the duo that transforms your crop

Well, if you’ve already mastered the basics and want to take it a step further, you need to create a controlled, stable, and consistent environment. This is where two key tools come into play: the plastic propagator and the heating mat. As you’ll see, the greenhouse will provide a closed and controlled environment, reducing the chances of contamination in the cake and promoting more consistent, easily controlled temperature and humidity levels.

On the other hand, the heating mat will help you achieve the ideal temperature for your mushrooms, especially during the colder months of the year. Together, they become an unbeatable team that helps you achieve better yields and avoid problems such as contamination or poor fruiting due to excessively low humidity or temperatures. These are its main features:

Propagator for mushrooms

Small, portable, and functional. The plastic propagator is like a luxury room for your mushrooms. Made of transparent plastic and featuring ventilation slots for improved gas exchange, it allows you to:

  • Maintain constant humidity inside (perfect for colonization and fruiting).
  • Create a controlled microclimate.
  • Protect from drafts, insects, or external contamination.
  • Organize multiple trays or kits easily and conveniently.

The best part is that it’s compact and affordable, ideal for placing anywhere with indirect light and relaxing while watching your mushrooms grow. No DIY or complicated installation required; just place it in the ideal spot and you’re ready to grow. Just remember to disinfect it thoroughly inside and out with isopropyl alcohol before you begin.

Mini plastic greenhouse and heating mat

With the propagator and heating mat kits, you have everything at your fingertips to achieve better yields

Heating mat

If the propagator is the room, the heating mat is the invisible heater that ensures the temperature never drops below the desired level. It’s especially useful in winter or in cold homes, where the thermometer can drop to temperatures that inhibit mushroom development—in other words, fruiting. With a heating mat, you can:

  • Distribute heat evenly from below.
  • Keep substrates active and stimulate fruiting.
  • Avoid temperature fluctuations that stress the mycelium and impair mushroom growth.

In addition, a mat of this type consumes very little electricity, takes up just the right amount of space, and you can place it directly under the greenhouse or growing trays to achieve that perfect temperature that will allow your mushrooms to develop without problems.

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Tips and tricks for growing mushrooms in a propagator with a heated mat

Now that you have the complete equipment, it’s time to get the most out of it. Here are some tips to help you optimize your grow in record time:

  • Place the mat on an insulating base (such as thick cardboard or wood) to prevent heat loss downwards.
  • Unless ambient temperatures are very low, try not to place the propagator directly on the cover: use a grid or elevate it slightly (1-2 cm will suffice) to avoid direct heat and prevent excessive condensation inside. Four bottle or jar stoppers, one in each corner of the propagator, are usually enough to slightly elevate it so it’s not in direct contact with the mat.
  • Use a digital hygrometer and thermometer inside the propagator. Keep in mind that some thermohygrometers with probes only measure temperature through the probe; if you also want to know the humidity inside the propagator, you’ll need to place the entire device inside.
  • Spray the inside of the propagator (never directly on the cake) to maintain humidity without saturating it. Once or twice a day is sufficient, although this depends on factors such as ambient temperature and humidity. If you struggle to reach a certain level of humidity, adding a little water to the bottom of the propagator will help you achieve it, especially if you use a heating mat.
  • Ventilate briefly once or twice a day to refresh the air and reduce CO₂ buildup inside the propagator.
  • If the mat doesn’t have a thermostat, keep an eye on its usage time: in spring or autumn, you may only need to turn it on at night, or you may even want to cover it with some material to reduce the heat generated a little and achieve the ideal temperature in the propagator.
  • You can leave the propagator vents open to improve ventilation, but then it’s best to cover them with a material that prevents any kind of contamination from entering. To cover them, you can use some type of surgical tape (Micropore) or filter netting (the kind used in aquariums).

With these practices, you’ll not only improve your results, but you’ll also have a much more stable, controlled, and repeatable crop, without environmental conditions having as much impact on the performance of your cakes.

Mushroom cake ready for harvest

Having more control over the mushroom environment leads to more generous fruiting

Conclusion: When your mushrooms ask for something more

Growing mushrooms is an addictive hobby, yes, but it’s also a small, home-grown science that becomes more enjoyable the more you control it. If you’ve already moved past the “first kit on the radiator” phase, the natural next step is to incorporate tools that give you autonomy and save you trouble. And if they’re also as economically viable as the ones we’ve presented to you today, it would be a shame to do without them.

The propagator and the heating mat are two discreet but incredibly effective allies. They not only make growing easier, but they also give you back control of your environment and allow you to focus on what matters: proudly watching your mushrooms grow.

Because yes, you can grow without them. But with them, you grow better, have better yields, and have a lower chance of contamination. The choice is yours!

Happy harvest!

The post Growing mushrooms in a propagator with a heating mat appeared first on Alchimia blog.

Hawaii Senate Hearing Garners Overwhelming Support for Psilocybin Bill

9 February 2023 at 08:00

Sen. Ron Kouchi introduced Senate Bill 1454 on Jan. 25, which was unanimously passed in the Hawaii Senate Committee on Health and Human Services (HHS) on Feb. 6. If the bill becomes law, it would establish a “therapeutic psilocybin working group” (managed by the Office of Wellness & Resilience [OWR]) to “Examine the medicinal and therapeutic effects of psilocybin or psilocybin-based products vis-à-vis mental health including post-traumatic stress disorder, depression, anxiety, and end-of-life psychological distress.”

The group would also be tasked with evaluating how markets such as regulators in Oregon and Colorado are tackling their own state psilocybin programs, with the goal of developing a comprehensive approach for Hawaii. In effect, the place would ensure that psilocybin access is safe, accessible, and affordable for patients.

During the hearing on Feb. 6, numerous testimonies were presented in favor of passing the bill to allow psilocybin access. The HHS compiled these testimonies on a 117-page document, which included a variety of speakers, beginning with a statement from Tia Roberts Hartsock, Executive Director of the OWR with the Office of the Governor. “As negative impacts of the COVID-19 pandemic continue to show up in our daily lives, promising interventions for mental health disorders should be included in conversations relating to trauma,” Hartsock wrote. “To make informed decisions on how we should address and resource attention on complex social issues like mental health disorders, research needs to be examined. The OWR supports the purpose of SB1454 to establish a working group to provide recommendations on their findings on the potential benefits of the therapeutic use of psilocybin.”

The Drug Policy Forum of Hawaii Board President, Nikos Leverenz, also expressed support for the bill. “Hawai῾i should endeavor to work more proactively in creating a climate that is conducive to allowing qualified medical professionals to use psilocybin as a therapeutic tool for those who could benefit from its supervised use,” Leverenz said.

Patients who had personal experiences with plant medicine treatments also shared how the bill could help countless others. “l can attest without hesitation that plant medicines are both safe and effective means by which to address and recover from intense psychological and physical trauma,” said Wyly Gray, Executive Director of Veterans of War. “Veterans of War sees firsthand the healing potential of these ancient medicines day in and day out, and we advocate strongly for their decriminalization on behalf of a nation of veterans suffering from the after-effects of war, as a group, we deserve a safe and effective path towards recovery; as a group, we simply want to come home. This is bigger than the failed War on Drugs; lives are lost every day.”

This year has been productive for Hawaii legislators looking into plant medicine and legalization. On Jan. 11, Rep. Jeanné Kapela spoke about introducing an adult-use cannabis bill. “We all know, and Hawaii’s people know, that it is high time to legalize recreational cannabis use for adults in Hawaii. This year we stand on the precipice of history,” Kapela stated. “Following the recommendations of a task force devoted to addressing cannabis policy, we now have a roadmap for legalizing recreational cannabis in our islands.” Kapela has not yet introduced her bill, but she explained that it would include a mass expungement program. “Social equity. People. That is what forms the heart of our proposal,” she explained.

The people of Hawaii also recently showed support for cannabis legalization through a poll conducted by the Hawaii Cannabis Industry Association. The survey revealed that 52% of Hawaii residents are in favor of legalization (with 31% saying they are opposed).

The post Hawaii Senate Hearing Garners Overwhelming Support for Psilocybin Bill appeared first on High Times.

Bad trips and magic mushrooms

7 February 2023 at 02:30

Bad trips within the psychedelic world are extremely intense personal experiences at the moment. If you don’t know how to act, it could easily generate more anxiety, which will only make the situation worse. In this post, we explain the nature of these trips, what to do if you enter a destructive thought loop during the session and what products you can use to try to stop them.

Sometimes a magic mushroom trip can be a strange, even unpleasant experience.

Sometimes a magic mushroom trip can be a strange, even unpleasant experience

What is it and what can cause a bad mushroom trip?

hallucinogenic mushroom trip is a very spiritually intense experience, where certain deep thoughts come to light, which if you know how to deal with them correctly, can mean a substantial change to your day-to-day life outside of the session. However, hallucinogenic mushrooms, like all mind-altering substances, are never used to solve internal problems; If these problems exist at the time of consumption, it is most likely that they will come to light magnified and without being able to find an answer.

But as some guy’s uncle would say, “With great power comes great responsibility.” In the end, what psilocybin does is act on the brain, generating extreme realities (magnified or reduced) about what we think or perceive through the senses. That is, everything that psilocybin can positively generate is controllable and produced by oneself, in the same way, that all negative thoughts, within the session, are produced and controlled by oneself.

It should be noted that a bad mushroom trip is very difficult to happen. Some reasons and preventions will be explained below to mitigate the chances of them happening, but it is a situation that affects a very small percentage of consumers.

The best way to avoid a bad trip is to be aware of when you take psilocybin, where, and with whom.

In no case do we want to put fear in the body when consuming them, since it is a key point when taking ‘shrooms; do it without fear and letting the new sensations invade your body, without prejudice.

Everyone can have a bad trip one day, even good old Beavis

Everyone can have a bad trip one day, even good old Beavis

In all cases, “a bad trip” is the subconscious mind’s way of displaying past or present life factors that need to be faced and dealt with, but that the conscious part is not ready for.

It usually starts with dark and disturbing thoughts coming from the subconscious. These thoughts gain strength until they become the existing reality. They become strong and powerful enough to not be able to think about other things and they stay in a loop.

A bad trip is at no time due to a physiological excess of the body towards psilocybin, but a mental reaction (conscious and subconscious) where the traveler is overwhelmed by the situation and negative thoughts. Although a “bad trip” can be intense at the time, it is important to remember that:

  • Psilocybin is toxicologically one of the safest substances
  • The experience is temporary
  • A “bad trip” can be psychologically beneficial in the long run

Some of the most recurring thoughts are usually:

  • Fear of staying in that state for life
  • Imagine fictitious situations in which everything goes against the consumer
  • Modify the existing reality perceiving that the whole world is against you
  • Seeing disturbing faces in places where they are not (pareidolia)
  • Looping thoughts
“Oh a demon face? That's interesting, thanks for showing me”

“Oh, a demon face? That’s interesting, thanks for showing me”

Now a couple of scientific facts:

Despite the harshness of the moment, a study on “bad trips” conducted at Johns Hopkins University has shown that 84% of the participants, when interviewed 6 months after the experience, said they had benefited from the “bad trip”, even if it was one of the most difficult experiences of their life.

Regarding medical assistance, the risk exists, although it is extremely insignificant. The 2017 Global Drug Survey found that 0.2% (2 in 1,000) of psilocybin mushroom users reported seeking emergency treatment after taking psilocybin mushrooms. This figure was comparatively 1.3% for alcohol and 4.8% for amphetamines. In these data, the little information about psilocybin should be taken into account, that in certain aspects of the trip, there may be sensations where the user is not comfortable and goes to the hospital, but these are completely normal and controllable if you have adequate information.

How to prevent a bad trip?

The most effective way to avoid having bad trips is the one that has been discussed throughout the post: being aware of the personal moment that one is going through and the space in which the trip will take place. This is called SET & SETTING. SET is the personal moment and SETTING is external stimuli, both the space and the company.

A trip can vary depending on several aspects, offering one type of experience or another

A trip can vary depending on several aspects, offering one type of experience or another

It is just as important to be aware of the moment one is going through as well as the company and the place where it will take place.

BE AWARE about:

  • The mood and mentality of the person ingesting the substance

  • The environment in which the substance is used

  • Whether the user is alone or with others

  • What experience does the user have with the substance and amount that they want to take?

  • Preconceptions and expectations of the user about the experience

If a person wants to experience the sensation of a psychedelic trip for the first time, it is recommended that they prepare an appropriate and safe space, since it can be key to the proper development of the session. A familiar, safe environment without factors that can cause negative thought patterns in the user is usually indicated. Try to avoid potentially noisy, messy, or public environments, the more messy and chaotic the space the more chaotic the experience; at this point, irrelevant people are included (people who sleep in the same house, friends who are not understanding the subject, etc.).

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Finally, try to be completely free of responsibilities during the trip and the next day. The easiest tasks can become extremely difficult, creating stress during the trip. Having a person who is knowledgeable about the subject act as a sober caregiver can be a great help for the smooth running of the session.

Another key point, discussed above, is the amount of psilocybin taken and the user’s experience with it (or with psychedelics in general). You must be clear about the appropriate dose for each person, in the same way, that you must know what variety of mushrooms you take.

There can be substantial changes between different varieties. These percentage changes in psilocybin can be very large, as species such as Panaeolus Cyanescens (Copelandia Hawaiian) can have up to four times more psilocybin than others. The Miraculix Psilo-Qtest for psilocybin is the perfect product to analyze the amount of psilocybin contained in the mushrooms that you wish to ingest.

A trip is a powerful and profound experience that should be treated with caution. However, there is a risk of having a challenging or negative experience. Luckily, there are strategies that we can use

A trip is a powerful and profound experience that should be treated with caution. However, there is a risk of having a challenging or negative experience. Luckily, there are strategies that we can use

What can I do to stop a bad magic mushroom trip myself?

If you are already on a bad trip, the most important thing is to calm down and turn the external situation around, to see if, by changing the external stimuli, the brain also begins to focus on thoughts that are not self-destructive or dark.

In the previous table, extracted from the same study on bad trips at Johns Hopkins University, the strategies used to try to improve the bad trip are reflected (in the gray bars). And in the crossed-out bars the people for whom the strategy worked. The conclusion that can be drawn is that there is no action that can stop the bad trip, it is rather a sum of all factors.

Change existing reality to change your thoughts

Based on your own experience and also on the research that has been done, there are certain things that usually work:

  • Move to a quiet place, with the minimum of external stimuli, or change the existing ones (change the music, go for a walk with a trusted person, etc.)
  • Focus on your own body, on your breathing, and be aware of your inhalations and exhalations.
  • Depending on the person, physical contact can help.
  • Accept the situation. You are in a not-pleasant moment but you can no longer do anything but accept it.
  • Trying to communicate with short phrases and simple words, the repetition of phrases that bring us comfort can be of great help.
In terms of medical emergencies, magic mushrooms represent a tiny percentage compared to other substances

In terms of medical emergencies, magic mushrooms represent a tiny percentage compared to other substances

Is there something external that stops the bad mushroom trip?

Once under the influence of psilocybin, or any other narcotic substance, it is very difficult to get out of it. In fact, it is one of the main reasons why bad trips can appear; when one wants to end the experience before the effects wear off. You must know the hours that the trip lasts and understand that it will go down, it is not eternal.

As with the effects of marijuana or alcohol (to name two of the most common), there is no substance that will make you sober, but there are certain foods that help. Well, the same thing happens with psilocybin. In general, they tend to be certain anti-stress substances, since stress is the maximum cause of this state. Among the most used can be found CBD, lavender supplements, or certain infusions.

Knowing these last points, we have put the Bad Trip Stopper on sale. It includes 6 units of four valerian capsules and two Dextrose tablets, designed to improve the bad state in which one is, relaxing the mind. First, take the capsules and then put the Dextrose tablets in your mouth, which dissolve little by little. Then try to eat something. This will help the body to return to a state of half normality.

Valerian acts as a tranquilizer, reducing stress since it acts as an inhibitor of neurons in the sympathetic nervous system. Dextrose is a simple sugar identical to glucose that is very quickly assimilated, providing extra sugar and energy, as well as mitigating the valerian taste.

The post Bad trips and magic mushrooms appeared first on Alchimia blog.

Tatandi, handmade and high quality Psilocybe kits

20 January 2023 at 04:23

Tatandi is the new brand of hallucinogenic mushrooms that has entered the Alchimia catalog, and we have thought it’d be nice to dedicate them a post, both because of the peculiar way this company works and because of the extensive catalog they offer to their customers, all of which are available at our online store.

This company based in Spain began to make its way in 2014 based on research and studies on mycology, a tough work that slowly turned into products from which to make a profit: hallucinogenic mushroom kits. Today we present them to you in this article.

Tatandi has been developing the best quality mushroom breads for nearly 10 years

Tatandi has been developing the best quality mushroom kits for nearly 10 years

Tatandi, their own work philosophy

All this adventure was started by just two people, a mycologist who specialized in the Psilocybe species and a designer of materials and supplies dedicated to the field of mycology.

From the very beginning, they directed the basic principles of the company towards the total satisfaction of the clients, working in the most personal and traditional way possible in order to adapt to the characteristics and needs of each one of them. In these last 8 years, they have not stopped trying to improve every day, being one of the few Spanish companies that have their own bioreactor specially dedicated to growing mushrooms, created by themselves.

They are proud to say that the kits they make are in vitro (also called 100% mycelium). They are made from completely natural and organic substrates, such as manure. All this is part of the process to ensure that the mushrooms obtain everything they need for optimum growth and development, with more than proven results.

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Tatandi’s Mushroom Kits Catalog

Despite all the positives mentioned so far, we have not yet reached the sweet spot within Tatandi. This is because the greatest incentive that this company has is the catalog. They have a catalog of Psilocybes that is unique in Europe, always looking for the most exotic varieties on the market (and abroad), but grown in their own way, with great respect and love for mushrooms. That is why we present some of the varieties that we have found most spectacular in Tatandi’s catalog:

Koh Samui Classic

This strain is one of the most distinctive, both in the way they grow and in the amount of psilocybin they produce. It was discovered by the famous endomycologist John Allen on the east coast of Thailand: Koh Samui. Specifically in the city of Hua Thanon.

Without a doubt, it is a variety that attracts attention due to the way it grows. The shrooms themselves are large, with a low foot in height but really wide, even exceeding the width of the cap. Once the growing medium is filled with Koh Samui Classic mushrooms it becomes a great sight to behold, as the stems grow until they come together and step on each other, creating an amalgamation of mycelium, feet, and hats.

The appearance of the Koh Samui Classic mushrooms is simply spectacular

The appearance of the Koh Samui Classic mushrooms is simply spectacular

Tatandi Leucistic

This was the first variety isolated by Tatandi through genetic isolation, and it has undoubtedly become one of the most sought-after in its catalog.

And it is that the popularity of Tatandi Leucistic has grown exponentially due to two simple but essential factors. It is an easy variety to grow, which will produce a large amount of magic mushrooms which generate an equally large amount of psilocybin.

Tatandi Leucistic's ease of cultivation makes her a favorite among novice growers

Tatandi Leucistic’s ease of cultivation makes it a favorite among novice growers

Yeti

There are certain varieties that cannot be missing in a catalog of hallucinogenic mushrooms, and among them is Yeti. It is a powerful variant of True Albino Teacher, currently one of the varieties with the highest psilocybin content on the market.

It produces large and corpulent specimens, with wide feet and a hat that takes on dark tones as it matures. As mentioned, it is one of the varieties with the highest psilocybin per gram ratio, so you’d better make responsible use of them!

Yeti is one of the magic mushroom varieties with the most psilocybin per gram on the market

Yeti is one of the magic mushroom varieties with the most psilocybin per gram on the market

Treasure Coast Albino

Variety of great power, especially in its visual effects. Isolated and crossed by the same mycologist who discovered the B+ variety, mr. G, it is the result of a hybridization between the original Treasure Coast with an albino variety. Treasure Coast genetics is generally a variety of slow cultivation, a characteristic that provides a higher density, and consequently a higher amount of psilocybin per mushroom.

One of the reasons why it is so rewarding to grow Treasure Coast Albino is because of its beautiful cultivation, full of contrasts. Its beautiful discoloration generates a beautiful festival of negatives when it comes together with its completely black spores.

The albino version of the Treasure Coast mushroom variety is as photogenic as it is potent

The albino version of the Treasure Coast mushroom variety is as photogenic as it is potent

But Tatandi’s extensive collection does not end here…Far from it! In addition to the varieties that we have highlighted, in our store you can also find the following:

  • Alcabenzi
  • Mexican
  • Golden Teacher
  • White Rabbit
  • Moby Dick
  • McKennai
  • Thai Pink Buffalo
  • Ecuador
  • Brazil
  • B+
  • Red boy
  • Rusty White
  • Blue Meanie

As always, we will be delighted if you share with us your growing tips, experiences and, of course, any doubts you may have about growing magic mushrooms or Tatandi varieties.

Happy growing!

The post Tatandi, handmade and high quality Psilocybe kits appeared first on Alchimia blog.

The Different Ways to Consume Magic Mushrooms

25 January 2023 at 11:29
ways to consume magic mushrooms

Image credit: Tania Malréchauffé via Unsplash

Magic mushrooms have enthralled people from all across the world for centuries. From their traditional use in religious ceremonies to recent reports of significant breakthroughs in psychedelic-assisted therapy, these mysterious fungi have been steeped in mystique and lore.

But, despite this historical and cultural curiosity, performing proper mushroom consumption can seem daunting even for experienced users because there is so much variety available.

This article aims to outline the various consumption methods, explore their advantages and disadvantages, and offer advice on selecting the right option based on individual needs and desired effects.

Whether you are a long-time fan or a curious first-timer looking to expand your knowledge of entertainingly enchanting fungi— we’ve got you covered.

 

Eating Raw

Eating raw magic mushrooms can be a challenging yet rewarding experience. Since the mushrooms are not processed, one has to ensure they are consuming a species of mushroom that is safe for ingestion.

For those willing to accept the risk, ingesting them raw can offer many benefits. The most significant benefit is that proper gut health naturally turns the psilocybin into psilocin, meaning one can entirely bypass necessary processing and conversion, accelerating desired effects.

Furthermore, eating them fresh allows you to savor the taste lost when using other consumption methods.

However, although this may be one of the safest methods to consume magic mushrooms, personal discretion must still be exercised, and it is recommended to use caution when ingesting anything in its natural form.

 

Brewing Tea

Brewing tea has become a popular way to consume magic mushrooms as it allows for dosage control and masks the earthy taste some users find unpleasant.

Brewing them as tea is simple: add the desired amount of dried mushrooms into hot water (not boiling), steep for 10 minutes, strain, and cool to an appropriate drinking temperature. The infused mushroom tea can be enjoyed as-is or with lemon and honey for added flavor.

Additionally, it can be poured into an ice cube tray and frozen so that users have pre-dosed servings to take at regular intervals throughout the day instead of consuming all the effects simultaneously.

Magic mushroom tea is a convenient way to reap their potential benefits and a great way to get creative in the kitchen.

 

how to consume magic mushrooms

Image credit: Bluebird Provisions via Unsplash

 

Making Capsules

Making mushroom capsules is a simple way to consume magic mushrooms without tasting the fungi. To make them, grind dried mushrooms into a fine powder using a coffee grinder or food processor and fill empty capsules with the desired powder.

The process is quick and easy; however, it does not offer any additional advantages over other consumption methods.

If you want to make capsules, ensure you know where to buy magic mushrooms. Purchasing them in their raw form is the most economical way to make capsules but be sure that where you buy magic mushrooms is reputable and offers high-quality products.

 

Smoking

Smoking magic mushrooms is one of the fastest and most efficient ways to feel their effects. It can be done in many ways; some prefer grinding them into a fine powder and rolling them up with regular smoking paper, while others opt for adding dried mushrooms directly into joints or spliffs.

The advantage of this method is that it offers instantaneous effects due to the direct absorption of psilocybin into the bloodstream via the lungs.

However, smoking also has its downsides; consuming them through this method can produce a harsher and less enjoyable experience than eating or drinking them.

 

Vaping

Vaping is an increasingly popular way to partake in the effects of magic mushrooms. To make a vape, grind dried mushrooms into a fine powder and fill the chamber of any standard herbal vaporizer.

Vaping offers several advantages; it has been shown to reduce exposure to harmful carcinogenic toxins produced by smoking while providing more potent effects due to the conversion of psilocybin into psilocin that occurs as a result of heating. Additionally, vapes are convenient and easily transportable, making them ideal for anyone on the go.

Vaping, compared to smoking, is a more enjoyable experience due to the lack of harshness and taste, although the lack of visible smoke produced may put some people off.

 

Oral Spray

Oral sprays are becoming increasingly popular as an efficient method for consuming magic mushrooms. It involves extracting psilocybin molecules from dried mushrooms using a liquid like ethanol or vegetable glycerin, then adding them to a spray bottle containing this same liquid.

The user sprays the desired amount of liquid into their mouth and swallows it; the effects will begin to be felt after around 20 minutes.

This method is attractive to those who don’t like the taste of mushrooms and want immediate results. However, the effects may not be as strong as those obtained from eating or drinking due to the body’s ability to break down psilocybin molecules during digestion.

 

ways to take magic mushrooms

Image credit: Adrian Infernus via Unsplash

 

Cooking

Cooking with magic mushrooms is a great way to enjoy their potential benefits and to make them more palatable for those who may not be fans of their earthy taste. From brownies and cookies to gummies and chocolates, the possibilities are endless.

When cooking with magic mushrooms, you must understand how heat affects psilocybin, as it is sensitive to temperatures above 280°F. If your recipe calls for high-heat cooking, it is recommended to pre-cook the mushrooms before adding them to the dish to preserve their effects.

Arizona Bill Would Provide Grants for Magic Mushroom Trials

25 January 2023 at 08:00

Legislation proposed in Arizona would provide millions of dollars in grant funding to expand research into psilocybin––the primary psychoactive component in magic mushrooms––as a potential treatment for certain mental health conditions.

The bill, introduced by a Republican lawmaker and backed by Democrats, “would put $30 million in grants over three years toward clinical trials using whole-mushroom psilocybin to treat mental health conditions like depression and PTSD,” the Arizona Mirror reports

The outlet reports that one of the bill’s biggest backers is Dr. Sue Sisely, an internal medicine physician who believes that psilocybin treatment could be a boon for ailing military veterans. 

“It’s curbed their suicidality, it’s put their PTSD into remission, it’s even mitigated their pain syndromes,” Sisely said of patients she has seen benefit from psilocybin, as quoted by the Arizona Mirror. “It’s shown evidence of promoting neurogenesis (the growth and development of nerve tissue). There’s all kinds of great things that are being uncovered, but they’re not in controlled trials—they’re anecdotes from veterans and other trauma sufferers.” 

According to the Mirror, “so far the only controlled trials on psilocybin to treat medical conditions have used a synthetic, one-molecule version of the substance, which is vastly different from a whole mushroom, which contains hundreds of compounds.”

“These agricultural products are very complex, and that is what people are reporting benefit from,” Sisley told the Arizona Mirror. “Nobody in the world has access to synthetic psilocybin unless you’re in one of these big pharma trials.” 

In the last decade, psilocybin has gone from the fringes to the mainstream, as researchers and policymakers have grown more amenable to mushrooms as an effective treatment for a variety of different disorders. 

It has also become the next frontier for drug legalization advocates, as states like Arizona consider measures that would expand its usage. 

To the north of the Grand Canyon State, advocates in Utah have launched a campaign to push legislators to legalize psilocybin for clinical and academic purposes.

“Numerous robust studies have shown that psilocybin therapy is beneficial in reducing treatment-resistant depression, anxiety, addiction, trauma, obsessive-compulsive disorder, and other mental health disorders. It is more effective than synthetic pharmaceuticals by a large margin. Psilocybin has also shown effectiveness in easing fear and anxiety in people with terminal cancer. For instance, a groundbreaking study performed by John Hopkins Medicine found that psilocybin reported better moods and greater mental health after participating in a single clinical dose,” Utah Mushroom Therapy, the group behind the campaign, says in a statement.

The group is looking to gin up public support for the treatment after the state’s Republican governor, Spencer Cox, signed a bill last year establishing a task force that will study psilocybin as a mental health treatment.

Utah Mushroom Therapy says that, in the wake of the task force, “legalizing and decriminalizing Psilocybin in Utah is now very likely but still needs public support.”

“The use of mushrooms has been documented in 15 indigenous groups in America and various religious communities in Utah. This petition supports those groups who wish to use psilocybin safely, sincerely, and as a necessary part of their religion. The use of psilocybin does not contradict other Utah cultures and is protected by the first amendment as well as the Religious Freedom Restoration Act. This petition is to advocate Utah law to protect the religious rights of Utahns,” the group says

“Psilocybin is a natural, non-toxic substance. Despite this, it is currently a Schedule I substance. Scientists have demonstrated it has profound medicinal value and believe serotonergic hallucinogens assist cognitive processes and should be decriminalized. Psychedelics can change perception and mood, help people soften their perspective and outlook, and process events that may otherwise lead to substance abuse, trauma, and criminal behavior,” it continues.

The post Arizona Bill Would Provide Grants for Magic Mushroom Trials appeared first on High Times.

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