On December 4, WIRED sat down with some of the biggest names in tech, culture, business, and science for a day full of in-depth interviews.

George Foote, who served as the outside general counsel to the US Institute of Peace, said at WIRED’s Big Interview event that DOGE operatives arrived like a “strike team.”

At WIRED’s Big Interview event, the activist and organizer said he doesn’t “think the Chuck Schumers of the world understand” what’s coming for the party.

Big Tech has lost its way. At WIRED’s Big Interview event, Techdirt editor Mike Masnick and Common Tools CEO Alex Komoroske announced a manifesto designed to help the industry get back on track.

The cofounder and CEO of Circle says “money as an app platform” is the next step in a digital-based global economic system that’s right around the corner.

Sahil Lavingia, previously a DOGE operative at the Department of Veterans Affairs, is now a career employee at the IRS. He said at WIRED’s Big Interview event that he expects to work there 10 years.

People like to rag on the Bay Area, but mayor Daniel Lurie believes there’s no better place in the world than San Francisco.

The author of Super Agers believes AI could bring big changes to the world of medicine.

Cloudflare CEO Matthew Prince claims the internet infrastructure company’s efforts to block AI crawlers are already seeing big results.

The Trump administration might think regulation is killing the AI industry, but Anthropic president Daniela Amodei disagrees.

The Wicked: For Good director says being able to improvise on set allows for the kind of moments that are hard for machines to make.

Lisa Su leads Nvidia’s biggest rival in the AI chip market. When asked at WIRED’s Big Interview event if AI is a bubble, the company’s CEO said, “Emphatically, from my perspective, no.”

On this week’s episode of The Big Interview podcast, the philanthropist offers her insights on billionaire donors, kids on phones, and the importance of women’s health care.